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Issue 35, Previous Article Next Article. From the journal: Dalton Transactions. This article is Open Access. Please wait while we load your content Something went wrong.
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Download Citation. Dalton Trans. Indicators for neocortical latent factors in Fig. For comparative purposes, we also fitted an alternative model positing that common variance across the indicators Fig.
To reduce model complexity for the functional subdivisions and have a comparable number of regions of interest across functional loops Fig.
Given that the anterior cingulate cortex ACC is associated with both the limbic and associative loops, as described above, its first-order latent factor loads on both the limbic and associative factor.
Again, for comparative purposes, we fitted an alternative model positing that common variance across the indicators Fig. In the next step, the latent factors of the corticolimbic subdivisions were related to the corresponding BP ND values for ventral, associative, and sensorimotor striatum.
Whenever a particular striatal subdivision of interest was associated with multiple corticolimbic factors, we report associations adjusted for the other two subdivisions to determine the unique links.
Residual variances, which are variances not explained by the latent factors, were allowed to covary between neighboring brain areas in all models Figs.
We evaluated whether the models provided a good representation of the data, using the root mean square error of approximation RMSEA and the comparative fit index [CFI; see Kline , for interpretation of these indices ].
All variables displayed acceptable skewness and kurtosis i. In all analyses, the alpha level for statistical decisions was set to 0. The corresponding numbers for data based on FBP reconstruction were highly similar Figure S2.
Note, however, that B max values varied largely across frontal regions Table S2 in supplementary. B max of the superior frontal cortex was five times greater than B max in the medial and three times greater than B max in the orbitofrontal cortex, suggesting an overestimation of the superior frontal cortex.
Notably, the positive correlation between our BP ND estimates and both post-mortem and [ 18 F]fallypride data occur despite differences in ROI definition.
Data from Seaman et al. FC frontal cortex superior, medial, oribital , TC temporal cortex superior, middle , EC entorhinal cortex, CC corpus callosum, ACC anterior cingulate cortex, PCC posterior cingulate cortex, Hc hippocampus, PHc parahippocampus, Amy amygdala, Pt putamen, Cd caudate, NAc nucleus accumbens, GP globus pallidus, TH thalamus.
FC frontal cortex Hall superior, medial, orbital in a and b , Seaman middle, superior, and inferior frontal gyrus, in c and d , COBRA superior frontal gyrus, rostral middle-frontal gyrus, medial orbital frontal cortex in a and b and superior frontal and rostral middle-frontal gyrus in c and d , TC temporal cortex Hall superior and middle-temporal cortex in a and b , Seaman superior, middle, and inferior temporal gyrus in c and d , COBRA superior and middle-temporal gyrus ; EC entorhinal cortex, CC corpus callosum, ACC anterior cingulate cortex, OFC orbitofrontal cortex Seaman , anterior, medial, lateral, and posterior orbital gyrus, COBRA medial orbital frontal cortex , PCC posterior cingulate cortex, Hc hippocampus, PHc parahippocampus, Amy amygdala, Pt putamen, Cd caudate, NAc nucleus accumbens, GP globus pallidus, TH thalamus.
Finally, Figures S3 and S4 illustrate similarities in time—activity curves and kinetics for regions with high striatum and low receptor density frontal cortex , as compared to the reference region.
A model representing striatal, limbic, and neocortical second-order latent factors Fig. Correlations among indicators for this model are also shown in Table S4.
Standardized factor loadings of the indicators for the first-order factors were high, reflecting high correlations between hemispheres.
Similarly, the first-order factors loaded highly on the second-order factors, indicating high correlations among hierarchically organized striatal, limbic, and neocortical regions.
This suggests that, despite the high correlation between the limbic system and neocortex, these two factors are separable. To test whether between-person differences generalize across the indicators, we also fitted a model in which all indicators load on one general factor.
Latent means for first-order factors of the model shown in Fig. A model postulating a functional subdivision of limbic and neocortical regions Fig.
Again, factor loadings for the first-order factors were high, reflecting high correlations between hemispheres. With respect to second-order factor loadings, ACC had equally high loadings on the limbic and associative factors, which is in line with its structural and functional associations in the brain Haber et al.
All other limbic, associative, and sensorimotor first-order factors loaded well on their respective second-order factors. Next, we correlated the latent factors Fig.
We investigated the distribution and interregional associations of [ 11 C]raclopride BP ND across the brain in a sample of older adults.
Importantly, we extended that study by showing that the data are organized according to known dopaminergic pathways across the striatum and cortex limbic, associative, and sensorimotor , and by showing specific associations between the corresponding striatal and cortical functional divisions.
However, recent studies provided evidence of good test—retest reliability for raclopride in extrastriatal regions Alakurtti et al. First, we show that [ 11 C]raclopride BP ND in extrastriatal regions is correlated with post-mortem Hall et al.
The good model fit indicates both convergent and discriminant validity, as the organization of [ 11 C]raclopride BP ND is in line with anatomical and functional DA pathways.
Convergent validity is supported by the higher associations among regions that should, according to theory, correlate with each other i.
At the same time, discriminant validity is supported by relatively weaker associations among regions that, according to theory, should be less strongly correlated.
Further, the fact that the left and right hemisphere show such strong correlations, resulting in very high first-order factor loadings around 0.
Our SEM analyses demonstrate good fit for a model assuming separate factors for striatal, limbic, and neocortical BP ND , which are positively correlated.
The link between the limbic system and neocortex was particularly high, which may be due to both being innervated by the VTA via the mesocortical and mesolimbic pathways Fig.
Importantly, our data are in line with a study using the high-affinity ligand [ 18 F]fallypride Zald et al. Thus, our conclusions regarding the anatomical factor structure based on extrastriatal [ 11 C]raclopride data are highly similar to those derived from [ 18 F]fallypride data.
Furthermore, the structure of individual differences suggests that neocortical and limbic BP ND data are organized in accordance with functional subdivisions of the DA system limbic, associative, sensorimotor.
The association between the limbic and associative factors was reliably lower than that between the associative and sensorimotor factors.
This likely reflects common dopaminergic innervation from the substantia nigra for the latter two cortical subdivisions Martinez et al.
By contrast, mesolimbic and mesocortical areas both receive input from the VTA Fig. The functional subdivision pertaining to the corticolimbic BP ND data is further supported by the specificity of correlations for the limbic and associative factors with the corresponding striatal subdivisions.
For the sensorimotor striatum, positive associations were observed with both sensorimotor and limbic regions.
The latent correlations between the limbic and sensorimotor factors were high as well. As noted by Trifilieff and Martinez , the sensorimotor striatum shares histochemical features with the ventral striatum Fudge and Haber and receives glutamatergic input from amygdala and other limbic regions Fudge and Haber ; Fudge et al.
DA-PET studies are typically characterized by relatively small sample sizes, which preclude examining interregional correlations of BP ND values in latent space.
The observed interindividual differences in anatomical and functional DA pathways in the current sample likely originate from genetic influences that are further augmented by recursive relations between epigenetic and environmental factors that operate across the lifespan Beam and Turkheimer Research shows that different interventions, such as cognitive training and physical exercise, can have selective effects on different parts of the DA system.
These genetic effects may become magnified in aging Papenberg et al. The novel models proposed may prove useful when investigating selective decline within and across pathways associated with the discussed genetic and lifestyle factors, but also in healthy aging Bäckman et al.
The data sets generated and analyzed during the current study are available from the corresponding author on reasonable request.
The Social Cognition Center Cologne SoCCCo provides a dynamic research environment for the psychological study of human social behavior with an emphasis on underlying social cognitive processes.
Ten research groups study a broad array of topics in social cognition, ranging from the dynamics of self-control to the ubiquity of social comparison and the intricacies of processing valenced information.
SoCCCo aims to conduct high-quality research, and provide a dynamic and inspiring research environment for all researchers regardless of seniority, gender, sexual orientation, ethnicity, nationality, or disabilities.
For more information on our ideals, click here. Dec 9, wissenschaftskommunikation. Op-ed by Laura König and Jan Crusius.
Ist das so schlimm? Is that so bad? May 25, RTL aktuell Forschungsprojekt zur Unterstützung im Umgang mit den psychologischen Belastungen durch COVID [Research project to support coping with COVID stress] News coverage of research by Andreas Glöckner.
May 19, WDR Warum wir wütend werden, wenn andere die Regeln brechen [Why we get angry when others break the rules] Interview with Andreas Glöckner on social distancing norms by Anastasiya Polubotko.
May 11, Radio Eins Die neue Sorglosigkeit [The new nonchalance] Interview with Andreas Glöckner on Corona risk fatigue. May 11, rtl. Süddeutsche Zeitung , Stern , Die Zeit , MSN , Augsburger Allgemeine.
Feb 19, Wissenschaftskommunikation. November 11, Junior Researcher Programme News How does the replication crisis affect public trust in psychology?
But can that trust be build back up? May 8, wissenschaftskommunikation. How powerful people react in moral dilemmas Blog post covering a publication by Alexandra Fleischmann , Joris Lammers , Paul Conway, and Adam D.
Galinsky By Alexandra Fleischmann. Apr 13, SPEKTRUM Dürfen wir stolz sein? Welcome to the Social Cognition Center Cologne. Nine Research Groups study a broad array of topics in Social Cognition.
Acceptance and adoption of protective measures during the Covid pandemic: The role of trust in politics and trust in science.
A motivational framework of social comparison. Journal of Personality and Social Psychology. Weiss, A. Trust in everyday life.
Froehlich, L. Similarity predicts cross-national social preferences. Social Psychological and Personality Science. The casket of Paul Cary rests in the back of an Ambulnz ambulance at Newark International Airport where his body will be flown back to his home state of Colorado on May 3, Amid concerns of the spread of COVID, Curtis Sulcer wipes down an escalator for shoppers at the North Park Mall in Dallas, Saturday, May 2, Texas charged into its first weekend of re-opening the economy with residents allowed to go back to malls, restaurants, movie theaters and retail stores in limited numbers.
Tymber Bryant, left, and Jackie Baker, with the Theater Tactical Signal Brigade of the South Carolina National Guard in Spartanburg, place food in the car of Sterling Crawford of Abbeville, food from Second Harvest Food Bank of Metrolina at the Department of Social Services Abbeville County Government Buildings in Abbeville, S.
Donal Dickens, the Williamston Branch Manager of Second Harvest Food Bank of Metrolina said there was enough food for three days for families who drove through, which ran out in two hours.
United States Postal Service mail carrier Frank Colon, 59, delivers mail amid the coronavirus pandemic on April 30, in El Paso, Texas.
Everyday the United States Postal Service employees work and deliver essential mail to customers. Medical workers take in patients outside of a special coronavirus intake area at Maimonides Medical Center on May 01, in the Borough Park neighborhood of the Brooklyn borough of New York City.
Hospitals in New York City, which have been especially hard hit by the coronavirus, are just beginning to see a downturn in COVID cases.
Navy hospital ship USNS Comfort prepares to depart Manhattan's West Side to return to Naval Station Norfolk in Virginia on April 30, in New York City.
The USNS Comfort, a floating hospital in the form of a Navy ship, is departing New York after the last patient aboard was discharged earlier this week.
The Comfort's 1, beds and 12 operation rooms were deployed to ease pressure on New York hospitals amid the coronavirus pandemic.
Pedestrians walk past a sign in front of the The Anthem, a popular live music venue, displaying a message of support amid the coronavirus pandemic, on April 29, , in Washington, DC.
Richard Frady of Hartwell, Georgia, a recovering COVID patient in the Intensive Care Unit at AnMed Health in Anderson, waves a "Can't Wait to be Home!
Tuesday, April 28, Phoenix Fire Department engineer Jake Fierros, left, receives a free antibody test for the new coronavirus, administered by Phoenix Fire Department engineer paramedic Johnny Johnson at the Phoenix Fire Department training facility in Phoenix on April 28, Antibody tests, do not test for the presence of COVID itself, but detect whether someone has the antibodies in their immune system to fight off the virus.
Within ten minutes after taking the test that first responder was notified by phone if they tested positive. The tests available to all members of the Phoenix Fire Department were organized by the United Phoenix Firefighters Association.
A person wears a mask to protect against the coronavirus, votes in the Ohio primary election at the Hamilton County Board of Elections on Tuesday, April 28, , in Norwood, a suburb of Cincinnati.
AnMed Health staff and bystanders take photos and video of F planes from The South Carolina Air National Guard th Fighter Wing flying over the hospital in Anderson, S.
Monday, April 27, The group stated they "are humbled by the sacrifices made from our first responders and healthcare professionals.
As our jets return from a training mission late Monday morning, 27 April, our six-ship formation of Swamp Fox F fighter jets will split off into three groups, with each group flying over different regions of the state in a display of national thanks to all who are fighting the good fight.
We wish we could flyover everyone who are contributing to winning the fight against COVID A waiter at Gloria's Latin Cuisine in serves up lunch to patrons on the patio in Colleyville, Texas on April 27, Shelley Craft, owner of The Men's Refinery BarberSpa gives a haircut to Kenneth Gregory at her salon in Augusta, Ga.
Vehicles line up to receive food during a donation drive by World Central Kitchen in the parking lot of the Camden Yards Sports Complex, Saturday, April 25, , in Baltimore.
World Central Kitchen conducted its food relief operation during the coronavirus outbreak to help relieve food insecurity faced by Baltimore's vulnerable communities, at the request of Governor Larry Hogan.
Eric Jones, 15, bowls as his dad, Heath, watches in the backyard of their Oklahoma City home, Tuesday, April 21, Health and his son Eric built a bowling lane in their backyard so that Eric, a competitive bowler, could continue to bowl while bowling alleys are closed.
Edwar Johnson works on making protective masks in Warren, Mich. General Motors has about workers at the now-closed transmission plant in suburban Detroit.
Caskets of Muslims who have passed away from the coronavirus are prepared for burial at a busy Brooklyn funeral home on the first day of Ramadan on April 24, in New York.
Like the majority of New York City funeral homes, services that deal with the dead in New York's Muslim communities have been overwhelmed with the large number of deceased.
Around the world, Muslims are preparing to observe the holy month of Ramadan under severe restrictions caused by the coronavirus outbreak.
New York City, which has been the hardest hit city in America from COVID, is starting to see a slowdown in hospital visits and a lowering of the daily death rate from the virus.
Cars line up for food at the Utah Food Bank's mobile food pantry at the Maverik Center, Friday, April 24, , in West Valley City, Utah.
As coronavirus concerns continue, the need for assistance has increased, particularly at the Utah Food Bank. Fitness coordinator Janet Hollander, leads a session of Balcony Boogie from outside Willamette Oaks in Eugene, Oregon for residents sheltering in their apartments during the COVID shutdown Tuesday April 21, The staff of the senior housing center have modified some of the regular routines for residents, staging activities like morning stretches and aerobic opportunities while still observing social distancing protocols.
Sheila Parr and her daughters Violet Cann, left, 7, and Stella Cann, 5, donate food and toilet paper to the Little Free Library on Princeton Drive in Austin, Texas, on Tuesday April 21, In response to the coronavirus pandemic, many of the book exchange boxes around the U.
The Paterson fire department COVID EMS unit responds to a call for a person under investigation of having the coronavirus on April 16, Paterson has one of the highest coronavirus caseloads in N.
Alma Cropper, 84, left, is given a coronavirus test near her vehicle at a walk-up testing center, April 20, , in Annapolis, Md. According to the City of Annapolis Office of Emergency Management, the testing site began with a limited number of tests for people with symptoms on Monday.
CLARY, AFP via Getty Images. Clary, AFP via Getty Images. A deserted 42nd Street is seen in midtown New York on April 19, during the COVID, coronavirus epidemic.
A woman wearing a face mask to protect herself from the coronavirus carries balloons for a birthday party on April 18, , in Arlington, Virginia.
A pedestrian uses a face cover while walking in downtown Durham, N. Roy Cooper's stay-home orders remain in effect as the coronavirus has not yet reached its peak in the state according to some hospitals.
IMPD cadets salute during a traditional end of duty call for IMPD Officer Breann Leath, Thursday, April 16, A mourner attends the funeral of Saul Sanchez, a longtime JBS employee that died of the coronavirus disease, at Sunset Memorial Cemetery in Greeley, Colo.
Mike Lane, a gas station attendant, tries to protect himself the best way he can to avoid the coronavirus while working at a Sunoco in Ridgefield Park, N.
NJ is the only state with full service gas in the country. To reduce the number of times a patient's room door is opened and the amount of personal protective equipment required, nurses in the intensive care unit of MedStar St.
Mary's Hospital communicate through a window with an erasable whiteboard from a COVID patient's room on April 14, in Leonardtown, Maryland.
This trio finds ample room to walk through a Rochester, N. A woman gestures to a child in a protective face mask as a precaution against the coronavirus to pose for a photograph with the Rocky statue outfitted with mock surgical face mask at the Philadelphia Art Museum in Philadelphia, April 14, Finn, Thunder and Lego at the window of Ronald Boik visiting him as their owner Nicole George holds their leashes at the Cedar Woods Assisted Living in Belleville, Michigan on Saturday, April 11, Nicole and Tim George brought their three alpacas, Thunder, Finn and Lego to the nursing home to brighten up the day for some of the residents that live there.
Nozmi Elder, 70 of Dearborn and owner of Cedar Woods Assisted Living said most of the residents have been confined to their rooms for the past three weeks as precautions for the Coronavirus and thought the site of alpacas visiting them would lift their spirits.
Lisa Chamblee buys produce at Concord Market in Anderson, S. April 9, The market sells food and plants from local sources and is selling well according to the business.
A man wearing a mask walks by St. John's United Methodist Church COVID Cross of Hope in Anderson, S. The cross with royal blue ribbons for each diagnosed person in South Carolina started when there were cases, but as the cross was placed in front of the church Thursday morning, the cases in South Carolina are at 2, with 63 deaths.
Sandra Cooley waves from her window to the Easter Bunny as he visits Crimson Village assisted living community Thursday, April 9, The bunny came from Amediysis, a home health, hospice care and personal care company that serves Crimson Village.
The bunny stayed outside the building to ensure safety from COVID exposure to the residents. United Airlines' Terminal C is nearly empty at Newark Liberty International Airport in Newark, N.
Rabbi Dean Shapiro left of Temple Emanuel in Tempe, angles his laptop so others online can see their Seder plate as Shapiro's partner, Haim Ainsworth and their son, Jacob Shapiro-Ainsworth, 11, look on, as they participate in an online Seder during the first night of the Jewish holiday of Passover at their home in Tempe on April 8, The Seder which included members from Temple Emanuel was being held online because of the coronavirus pandemic.
First Responders gathered outside of Northern Westchester Hospital in Mount Kisco, N. Nurses in the emergency department of MedStar St. Mary's Hospital don personal protective equipment before entering the room of a patient suspected of having coronavirus April 8 in Leonardtown, Md.
A whimsical display fashioned like giant high-demand toilet paper rolls draws attention to Hub City Smokehouse's curbside service on Main Street in historic downtown Crestview, Fla.
A woman looks for a director after voting at Riverside High School in Milwaukee on April 7, The Wisconsin primary is moving forward in the wake of the coronavirus epidemic after Gov.
Sie haben ihre Brutplätze in Nord- und Osteuropa verlassen und sind auf dem Weg in wärmere Gebiete im Süden Europas.
Quarks zeigt, was Kaffee und Tee mit uns machen. Wie wirkt Koffein im Gehirn und was haben die Gene damit zu tun? Und hilft schwarzer Tee, der lange ziehen konnte, wirklich beim Einschlafen?
Magersucht, Bulimie, Binge-Eating: Essstörungen gehören in Deutschland zu den häufigsten psychischen Erkrankungen.
Doch wenn der eigene Körper zum Feind wird, dann fordert dieser Kampf Opfer: Die Lebensfreude, die Gesundheit oder sogar das Leben selbst.
Oft der allerletzte Ausweg: Der Gang in eine Klinik. Dabei sind seine Rollen vielfältiger und sein Leben komplizierter als es den Anschein hat.
Mit dem Teil-Lockdown im November wird die Kulturbranche erneut hart getroffen. Was ihm fehle, sei der Dialog mit der Politik.
Kultur sei kein Luxus, sondern ein Menschenrecht. Mit seinem neuen Buch "Im Tal und darüber hinaus" entwirft Dieter Jandt ein unsystematisches Stadtmosaik für seine Wahlheimat Wuppertal.
Von unfassbar schön bis irgendwie ziemlich seltsam: Das sind die Hits der 90er. Megastars wie Britney Spears und Robbie Williams starten ihre Karrieren.
Die Ärzte behandeln uns mit "Schrei nach Liebe" und Tic Tac Toe machen frechen Rap. Der Blick in die Regionen - nicht nur im Fernsehen, sondern auch im Netz.
Alle Ausgaben der Lokalzeit gibt es hier im Livestream. Fast vier Millionen Menschen schalteten im vergangenen Jahr täglich in Nordrhein-Westfalen das WDR Fernsehen ein.
Auch für die dritten Programme der ARD insgesamt war das Jahr sehr erfolgreich. Oder wie wir ihn nennen: Die Elefantenrunde.
Dafür haben wir unsere liebsten Politik-Podcaster:innen versammelt - und einen Ehrengast. Ab sofort ist es so weit: Die Videoangebote des WDR werden unter dem Dach der ARD Mediathek gebündelt.
Auch das Webangebot für Video-on-Demand VoD zieht nun um. Seit dem Wochenende November ist der WDR federführend für die ARD-Wintersport-Berichterstattung zuständig.
Wir waren bei der Premiere dabei. Erwachsensein nervt: Einkaufen, Arbeiten, Miete zahlen - manchmal fehlt der Durchblick. Nora und Sebastian von Economista, dem neuen Wirtschaftspodcast des WDR, suchen Antworten auf Fragen, die den Alltag junger Menschen bestimmen.
Die Corona-Berichterstattung von Tageszeitungen und öffentlich-rechtlichen Sendern wird gut oder sehr gut beurteilt. Die Herkunft eines Tatverdächtigen zu nennen, fällt Journalisten oft schwer.
Es gibt kein klares Ja oder Nein. Im WDR wird jeder einzelne Fall sorgfältig abgewogen. Und diesen Abwägungsprozess machen wir für Sie transparent und nachvollziehbar.
Texte in Leichter Sprache sind einfacher als andere Texte.
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